Trend Micro VSAPI 8.700.0.1004 in Trend Micro AntiVirus, when Internet Explorer 6 or 7 is used, allows remote attackers to bypass detection of malware in an HTML document by placing an MZ header (aka "EXE info") at the beginning, and modifying the filename to have (1) no extension, (2) a .txt extension, or (3) a .jpg extension, as demonstrated by a document containing a CVE-2006-5745 exploit.

VsapiNT.sys in the Scan Engine 8.0 for Trend Micro AntiVirus 14.10.1041, and other products, allows remote attackers to cause a denial of service (kernel fault and system crash) via a crafted UPX file with a certain field that triggers a divide-by-zero error.

TmComm.sys 1.5.0.1052 in the Trend Micro Anti-Rootkit Common Module (RCM), with the VsapiNI.sys 3.320.0.1003 scan engine, as used in Trend Micro PC-cillin Internet Security 2007, Antivirus 2007, Anti-Spyware for SMB 3.2 SP1, Anti-Spyware for Consumer 3.5, Anti-Spyware for Enterprise 3.0 SP2, Client / Server / Messaging Security for SMB 3.5, Damage Cleanup Services 3.2, and possibly other products, assigns Everyone write permission for the \\.\TmComm DOS device interface, which allows local users to access privileged IOCTLs and execute arbitrary code or overwrite arbitrary memory in the kernel context.