core/nicklist.c in Irssi before 0.8.15 allows remote attackers to cause a denial of service (NULL pointer dereference and application crash) via vectors related to an attempted fuzzy nick match at the instant that a victim leaves a channel.
Irssi before 0.8.15, when SSL is used, does not verify that the server hostname matches a domain name in the subject's Common Name (CN) field or a Subject Alternative Name field of the X.509 certificate, which allows man-in-the-middle attackers to spoof IRC servers via an arbitrary certificate.
The DCC ACCEPT command handler in irssi before 0.8.9+0.8.10rc5-0ubuntu4.1 in Ubuntu Linux, and possibly other distributions, allows remote attackers to cause a denial of service (application crash) via certain crafted arguments in a DCC command.
Multiple CRLF injection vulnerabilities in (1) ixmmsa.pl 0.3, (2) l33tmusic.pl 2.00, (3) mpg123.pl 0.01, (4) ogg123.pl 0.01, (5) xmms.pl 2.0, (6) xmms2.pl 1.1.3, and (7) xmmsinfo.pl 1.1.1.1 scripts for irssi before 0.8.11 allow user-assisted remote attackers to execute arbitrary IRC commands via CRLF sequences in the name of the song in a .mp3 file.