The (1) ListView, (2) ListView2, (3) TreeView, and (4) TreeView2 ActiveX controls in MSCOMCTL.OCX in the Common Controls in Microsoft Office 2003 SP3, 2007 SP2 and SP3, and 2010 Gold and SP1; Office 2003 Web Components SP3; SQL Server 2000 SP4, 2005 SP4, and 2008 SP2, SP3, and R2; BizTalk Server 2002 SP1; Commerce Server 2002 SP4, 2007 SP2, and 2009 Gold and R2; Visual FoxPro 8.0 SP1 and 9.0 SP2; and Visual Basic 6.0 Runtime allow remote attackers to execute arbitrary code via a crafted (a) web site, (b) Office document, or (c) .rtf file that triggers "system state" corruption, as exploited in the wild in April 2012, aka "MSCOMCTL.OCX RCE Vulnerability."

Microsoft Office 2010, SharePoint Enterprise Server 2010, SharePoint Server 2010, Web Applications, Office Web Apps Server 2010 and 2013, Word Viewer, Word 2007, 2010, 2013 and 2016, Word Automation Services, and Office Online Server allow remote code execution when the software fails to properly handle objects in memory.

Microsoft Visual Basic for Applications (VBA) contains an insecure library loading vulnerability that could allow for remote code execution.

A stack-based buffer overflow vulnerability exists in the parsing of RTF data in Microsoft Office and earlier allows an attacker to perform remote code execution.