The CtcpParser::packedReply method in core/ctcpparser.cpp in Quassel before 0.7.3 allows remote attackers to cause a denial of service (crash) via a crafted Client-To-Client Protocol (CTCP) request, as demonstrated in the wild in September 2011.
SQL injection vulnerability in Quassel IRC before 0.9.1, when Qt 4.8.5 or later and PostgreSQL 8.2 or later are used, allows remote attackers to execute arbitrary SQL commands via a \ (backslash) in a message.