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It was discovered that pyOpenSSL incorrectly handled memory when performing operations on a PKCS #12 store. A remote attacker could possibly use this issue to cause pyOpenSSL to consume resources, resulting in a denial of service.
This attack appear to be exploitable via Depends upon calling application, however it could be as simple as initiating a TLS connection that would cause the calling application to reload certificates from a PKCS #12 store. This vulnerability appears to have been fixed in 17.5.0.